Application and Dosing
Simple bedtime application for get-up-and-go sweat reduction the next day1,2
—commercially insured patients pay $0*
With unique features and one-pump-per-underarm dosing at bedtime—Sofdra is designed for easy axillary application2
during application
underarm every time
Formulated with your
patients in mind1:
- Aluminum-free
- Fragrance-free
- Gluten-free
- Paraben-free
- Propylene glycol-free
- Polyethylene glycol-free
See how Sofdra can fit
into your patients’
bedtime routine
View instructions for use
When your patients apply at bedtime, let them know2:
Before applying Sofdra
- Don't shave or apply deodorant to armpits within 8 hours of application
- Don't exercise, shower, or wash underarms within 30 minutes of application
While applying Sofdra
- Don’t smoke or go near an open flame until the gel is dry, as Sofdra gel is flammable
After applying Sofdra
- Let Sofdra gel dry for 5 minutes after it is applied
- Don’t put on clothing until the gel has dried completely
- Rinse the applicator and wash hands with soap and water after applying Sofdra
- Patients can shower 8 hours after applying Sofdra
can pay $0 for Sofdra
Indication
Sofdra™ (sofpironium) topical gel, 12.45% is an anticholinergic indicated for the treatment of primary axillary hyperhidrosis in adults and pediatric patients 9 years of age and older.
IMPORTANT SAFETY INFORMATION
Contraindications
Sofdra is contraindicated in patients with medical conditions that can be exacerbated by the anticholinergic effect of Sofdra (e.g., glaucoma, paralytic ileus, unstable cardiovascular status in acute hemorrhage, severe ulcerative colitis, toxic megacolon complicating ulcerative colitis, myasthenia gravis, Sjögren’s syndrome).
Warnings & Precautions
Urinary retention
Use Sofdra with caution in patients with a history or presence of documented urinary retention. Patients should discontinue use immediately and consult a healthcare provider should any signs or symptoms of urinary retention develop (e.g., difficulty passing urine, distended bladder).
Control of Body Temperature
In the presence of high ambient temperature, heat illness (hyperpyrexia and heat stroke due to decreased sweating) can occur with the use of anticholinergic drugs, including Sofdra. Patients should avoid using Sofdra if not sweating when in hot or very warm environmental temperatures.
Operating Machinery or an Automobile
Transient blurred vision may occur with Sofdra. If blurred vision occurs, discontinue use and avoid engaging in activities that require clear vision (e.g., operating a motor vehicle or machinery, performing hazardous work) until the symptoms have resolved.
Adverse Reactions
The most common adverse reactions (≥2%) are dry mouth, vision blurred, mydriasis, and urinary retention. The most common local skin reactions (≥2%) are pain, erythema, dermatitis, pruritus, irritation, and exfoliation.
Drug Interactions
Avoid coadministration of Sofdra with other anticholinergic medications (due to risk of increase in anticholinergic adverse effects) and drugs that are strong inhibitors of CYP2D6.
Please see full Prescribing Information.